Calcium Channel antagonist 6
Calcium Channel antagonist 6 (Compound 328) is a highly selective antagonist of voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. Calcium Channel antagonist 6 inhibits of neuron depolarization-induced Ca2+ influx. Calcium Channel antagonist 6 is promising for research of neuropathic pain[1].
Product Specifications
CAS Number
687568-35-0
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N1CCN(CC1)C(C2=C(C)C3=C(C=CC(S(=O)(N(CC)CC)=O)=C3)O2)=O)OCC
Molecular Formula
C21H29N3O6S
Molecular Weight
451.54
References & Citations
[1]Andreas P. Termin, et al. Heterocyclic derivatives for modulation of calcium channels. WO2006010008A1. 2006-01-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
N-type calcium channel
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