TRPML modulator 1
TRPML modulator 1 (compound A12) is a TRPML modulator that promotes autophagy. TRPML modulator 1 AC50 in the TFEB test is less than 2 mM[1].
Product Specifications
CAS Number
2171065-77-1
UNSPSC
12352005
Target
Autophagy; TRP Channel
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
O=S(NC1=C(N2CCN(CC2)C3=CC=C(C=C3F)Cl)C=CC=C1)(C4=CC=C(S(=O)(N(C)C)=O)C=C4)=O
Molecular Formula
C24H26ClFN4O4S2
Molecular Weight
553.07
References & Citations
[1]Jorge Garcia FORTANET, et al. Trpml modulators. WO. WO2021127337A1. 2020-12-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
042859 200 µL
TJP3, NT (TJP3, ZO3, Tight junction protein ZO-3, Tight junction protein 3, Zona occludens protein 3, Zonula occludens protein 3)
Sign In for Pricing
View Details 
MBS9316212-01 48 Well
Human Adipocyte enhancer-binding protein 1, AEBP1 ELISA Kit
Sign In for Pricing
View Details MBS9316212-02 96 Well
Human Adipocyte enhancer-binding protein 1, AEBP1 ELISA Kit
Sign In for Pricing
View Details MBS9316212-03 5x 96 Well
Human Adipocyte enhancer-binding protein 1, AEBP1 ELISA Kit
Sign In for Pricing
View Details