TRPML modulator 1
TRPML modulator 1 (compound A12) is a TRPML modulator that promotes autophagy. TRPML modulator 1 AC50 in the TFEB test is less than 2 mM[1].
Product Specifications
CAS Number
2171065-77-1
UNSPSC
12352005
Target
Autophagy; TRP Channel
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
O=S(NC1=C(N2CCN(CC2)C3=CC=C(C=C3F)Cl)C=CC=C1)(C4=CC=C(S(=O)(N(C)C)=O)C=C4)=O
Molecular Formula
C24H26ClFN4O4S2
Molecular Weight
553.07
References & Citations
[1]Jorge Garcia FORTANET, et al. Trpml modulators. WO. WO2021127337A1. 2020-12-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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