SGLT1/2-IN-8
SGLT1/2-IN-8 (compound 8) is a potent and orally active SGLT1/2 dual inhibitor with IC50 values of 4 nM and 1 nM, respectively. SGLT1/2-IN-8 exhibits anti-hyperglycemic effects and can be utilized in relevant research[1].
Product Specifications
CAS Number
2206679-16-3
UNSPSC
12352005
Target
SGLT
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
OC1=CC(C)=C(CC2=CC=C(CC3)C3=C2)C=C1[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
Molecular Formula
C22H26O6
Molecular Weight
386.44
References & Citations
[1]Kuo GH, et al. Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors. Bioorg Med Chem Lett. 2018 Apr 15;28 (7) :1182-1187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGLT1; SGLT2
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