BOMA
BOMA (Compound 7) is a potent and selective metabotropic glutamate receptor 5 (mGluR 5) antagonist with an IC50 value of 3 nM and an Ki value of 3 nM. BOMA is promising for research of various pain states, including acute, persistent and chronic pain, inflammatory pain and neuropathic pain[1].
Product Specifications
CAS Number
[540496-84-2]
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
N#CCC1=CC=C(C2=NC3=C(O2)C=CC=C3)C=C1OC
Molecular Formula
C16H12N2O2
Molecular Weight
264.28
References & Citations
[1]Wang B, et al. Discovery of novel modulators of metabotropic glutamate receptor subtype-5. Bioorg Med Chem. 2004 Jan 2;12 (1) :17-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR5
Curated Selection
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