O-2172
O-2172, a carbacyclic analog, is a DAT inhibitor, with IC50 values of 47 nM and 7000 nM for DAT and SERT, respectively[1].
Product Specifications
CAS Number
[521062-92-0]
UNSPSC
12352005
Target
Dopamine Transporter
Related Pathways
Neuronal Signaling
Field of Research
Others
Smiles
O=C(C(C1CCCC1)C2=CC=C(C(Cl)=C2)Cl)OC
Molecular Formula
C14H16Cl2O2
Molecular Weight
287.18
References & Citations
[1]Peter C Meltzer, et al. Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate. J Med Chem. 2003 Apr 10;46 (8) :1538-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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