N-Palmitoyl-phenylalanine

N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215) . N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 > 400 μM) but has no splicing activity in intact HeLa cells[1].

Product Specifications

CAS Number

[37571-96-3]

UNSPSC

12352211

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Purity

99.67

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCC(N[C@H](C(O)=O)CC1=CC=CC=C1)=O

Molecular Formula

C25H41NO3

Molecular Weight

403.60

References & Citations

[1]Kerstin A Effenberger, et al. The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes. J Biol Chem. 2015 Nov 13;290 (46) :27524-31.