N-Palmitoyl-phenylalanine
N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215) . N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 > 400 μM) but has no splicing activity in intact HeLa cells[1].
Product Specifications
CAS Number
[37571-96-3]
UNSPSC
12352211
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Purity
99.67
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCCCCCCCCCC(N[C@H](C(O)=O)CC1=CC=CC=C1)=O
Molecular Formula
C25H41NO3
Molecular Weight
403.60
References & Citations
[1]Kerstin A Effenberger, et al. The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes. J Biol Chem. 2015 Nov 13;290 (46) :27524-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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