N-Palmitoyl-phenylalanine
N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215) . N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 > 400 μM) but has no splicing activity in intact HeLa cells[1].
Product Specifications
CAS Number
[37571-96-3]
UNSPSC
12352211
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Purity
99.67
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCCCCCCCCCC(N[C@H](C(O)=O)CC1=CC=CC=C1)=O
Molecular Formula
C25H41NO3
Molecular Weight
403.60
References & Citations
[1]Kerstin A Effenberger, et al. The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes. J Biol Chem. 2015 Nov 13;290 (46) :27524-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6236220-01 0.1 mL
ZNF253 (Zinc Finger Protein 253, Bone Marrow Zinc Finger 1, BMZF1, BMZF-1, Zinc Finger Protein 411, ZNF411) (MaxLight 750)
Ask
View Details 
MBS6236220-02 5x 0.1 mL
ZNF253 (Zinc Finger Protein 253, Bone Marrow Zinc Finger 1, BMZF1, BMZF-1, Zinc Finger Protein 411, ZNF411) (MaxLight 750)
Ask
View Details F4149-03A-ML490 100 µL
FGR, NT (Proto-oncogene c-Fgr, Tyrosine-protein Kinase Fgr, P55-FGR, SRC2) (MaxLight 490) discontinued
Ask
View Details