PPI-1040
PPI-1040 is a synthetic PlsEtn, a precursor of plasmalogens. PPI-1040 is an orally available plasmalogen analog that increases plasmalogen in several peripheral tissues of Pex7 low allele mice. PPI-1040 has the potential to replace deficient plasmalogen and inhibit chondrodysplasia punctata (RCDP) .
Product Specifications
CAS Number
[1436673-69-6]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OC(CO/C=C\CCCCCCCCCCCCCC)COP1(NCCO1)=O)=O
Molecular Formula
C43H72NO6P
Molecular Weight
730.01
References & Citations
[1]Fallatah W, et al. Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata. Dis Model Mech. 2020 Jan 24;13 (1) :dmm042499.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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