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D-F07

D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces Apoptosis. D-F07 has antitumor activity[1][2].

Product Specifications

CAS Number

2361297-58-5

UNSPSC

12352005

Target

Apoptosis; IRE1

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1OC2=C(C3=C1CN(CC3)C)C=C(C(O)=C2C4OCCCO4)OC

Molecular Formula

C18H21NO6

Molecular Weight

347.36

References & Citations

[1]Shao A, et al. Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy. Mol Cancer Ther. 2020 Dec;19 (12) :2432-2444.|[2]Shao A, et al. IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy. Mol Pharm. 2022 Apr 4;19 (4) :1059-1067.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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