APJ receptor agonist 11
APJ receptor agonist 11 (Ex 174) is a APJ receptor agonist with IC50 values ranging from 0.01 nM to 10 nM. APJ receptor agonist 11 can be used in the study of cardiovascular diseases[1].
Product Specifications
CAS Number
[2135515-67-0]
UNSPSC
12352005
Target
Apelin Receptor (APJ)
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C1N=C(N(C2=C(CC)C=CC=C2CC)C(O)=C1C(N3CCC(C3)C4=NC=C(C=C4F)Cl)=O)C5=NN(C)C=C5
Molecular Formula
C28H28ClFN6O3
Molecular Weight
551.01
References & Citations
[1]Zulan Pi, et al. 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as apj agonists. WO2017165640A1. 2017-09-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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