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APJ receptor agonist 11

APJ receptor agonist 11 (Ex 174) is a APJ receptor agonist with IC50 values ranging from 0.01 nM to 10 nM. APJ receptor agonist 11 can be used in the study of cardiovascular diseases[1].

Product Specifications

CAS Number

2135515-67-0

UNSPSC

12352005

Target

Apelin Receptor (APJ)

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C1N=C(N(C2=C(CC)C=CC=C2CC)C(O)=C1C(N3CCC(C3)C4=NC=C(C=C4F)Cl)=O)C5=NN(C)C=C5

Molecular Formula

C28H28ClFN6O3

Molecular Weight

551.01

References & Citations

[1]Zulan Pi, et al. 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as apj agonists. WO2017165640A1. 2017-09-28.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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