Epibatidine
Epibatidine is a α7nACh agonist with a Kd of 100 nM. Epibatidine can be used in the study of Alzheimer's, Parkinson's and schizophrenia[1].
Product Specifications
CAS Number
[140111-52-0]
UNSPSC
12352005
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
ClC1=NC=C([C@@H]2[C@]3([H])N[C@](CC3)([H])C2)C=C1
Molecular Formula
C11H13ClN2
Molecular Weight
208.69
References & Citations
[1]Thompson AJ, et al. The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology. 2017 Apr;116:421-428. doi: 10.1016/j.neuropharm.2017.01.008. Epub 2017 Jan 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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