Aurora A inhibitor 4
Aurora A inhibitor 4 (compound C9) is a potent inhibitor of Aurora A, with the GI50 of 4.26 and 7.08 μM in DU 145 cells and HT-29 cells, respectively[1].
Product Specifications
CAS Number
[371224-09-8]
UNSPSC
12352005
Target
Aurora Kinase
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C1N=C(NC(C1)C2=CC=C(C=C2)OC)NC3=NC(C)=C4C=C(OCC)C=CC4=N3
Molecular Formula
C22H23N5O3
Molecular Weight
405.45
References & Citations
[1]Mohammad Neaz Morshed, et al. Computational approach to the identification of novel Aurora-A inhibitors. Bioorg Med Chem. 2011 Jan 15;19 (2) :907-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aurora A
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