RBx-0597

RBx-0597 is a potent and selective DPP-IV inhibitor, demonstrating IC50 values of 32, 31, and 39 nM against human, mouse, and rat plasma DPP-IV, respectively. RBx-0597 shows potential for type 2 diabetes research[1].

Product Specifications

CAS Number

[929105-33-9]

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C(N1[C@@H](C[C@@H](C1)F)C#N)CN[C@@H]2[C@]3([H])[C@@]2([H])CN(C3)C(C4=CC=C(C=C4)F)=O

Molecular Formula

C19H20F2N4O2

Molecular Weight

374.38

References & Citations

[1]Singh S, et al. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes. Eur J Pharmacol. 2011 Feb 10;652 (1-3) :157-63.