PRMT5-IN-49

PRMT5-IN-49 (Compound 4b16) is an inhibitor of PRMT5[1].

Product Specifications

CAS Number

[428853-17-2]

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O=C(CCN1CC2=C(CC1)C=CC=C2)NC3=CC=C(C=C3)OC

Molecular Formula

C19H22N2O2

Molecular Weight

310.39

References & Citations

[1]Zhu K, et al. Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3693-3699.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT5

Available Sizes

Curated Selection

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