PRMT5-IN-49
PRMT5-IN-49 (Compound 4b16) is an inhibitor of PRMT5[1].
Product Specifications
CAS Number
[428853-17-2]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(CCN1CC2=C(CC1)C=CC=C2)NC3=CC=C(C=C3)OC
Molecular Formula
C19H22N2O2
Molecular Weight
310.39
References & Citations
[1]Zhu K, et al. Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3693-3699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT5
Available Sizes
Curated Selection
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