Lacripep
Lacripep is a synthetic tear protein. Lacripep binds to and activates syndecan-1 (SDC1) . Lacripep restores progenitor cell identity and epithelial barrier function. Lacripep resolves dry eye[1].
Product Specifications
CAS Number
[2243095-21-6]
UNSPSC
12352209
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Purity
97.74
Smiles
NC([C@H](CO)NC([C@H](CC1=CC=CC=C1)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](CO)NC(CNC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC(C)=O)CCCCN)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C106H167N27O29
Molecular Weight
2283.62
References & Citations
[1]Efraim Y, et al. A synthetic tear protein resolves dry eye through promoting corneal nerve regeneration. Cell Rep. 2022 Aug 30;40 (9) :111307.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2
Available Sizes
Curated Selection
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