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GABA-IN-4

GABA-IN-4 (Compound 17) is a N- (indol-3-ylglyoxylyl) benzylamine derivative. GABA-IN-4 exhibits high affinity for the benzodiazepine receptor (BzR) (binding site in GABAA receptor complex) with Ki value of 67 nM. Benzodiazepines are widely used as antianxiety, sedative-hypnotic and anticonvulsant agents[1].

Product Specifications

CAS Number

[61-38-1]

UNSPSC

12352101

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C=C3)Cl

Molecular Formula

C17H13ClN2O2

Molecular Weight

312.75

References & Citations

[1]Da Settimo A, et al. Synthesis, structure-activity relationships, and molecular modeling studies of N- (indol-3-ylglyoxylyl) benzylamine derivatives acting at the benzodiazepine receptor. J Med Chem. 1996 Dec 20;39 (26) :5083-91.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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