GABA-IN-4
GABA-IN-4 (Compound 17) is a N- (indol-3-ylglyoxylyl) benzylamine derivative. GABA-IN-4 exhibits high affinity for the benzodiazepine receptor (BzR) (binding site in GABAA receptor complex) with Ki value of 67 nM. Benzodiazepines are widely used as antianxiety, sedative-hypnotic and anticonvulsant agents[1].
Product Specifications
CAS Number
[61-38-1]
UNSPSC
12352101
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C=C3)Cl
Molecular Formula
C17H13ClN2O2
Molecular Weight
312.75
References & Citations
[1]Da Settimo A, et al. Synthesis, structure-activity relationships, and molecular modeling studies of N- (indol-3-ylglyoxylyl) benzylamine derivatives acting at the benzodiazepine receptor. J Med Chem. 1996 Dec 20;39 (26) :5083-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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