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CDK8-IN-17

CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC50 value of 9 nM, which can be used in cancer research[1].

Product Specifications

CAS Number

451458-32-5

UNSPSC

12352005

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1C2=C(N=C(N1C3=CC=C(CC)C=C3)SCC4=C(C)C=CC=C4)NN=C2

Molecular Formula

C21H20N4OS

Molecular Weight

376.47

References & Citations

[1]Wang T, et al. Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening[J]. European journal of medicinal chemistry, 2017, 129: 275-286.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK8

Available Sizes

Frequently Asked Questions

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