CDK8-IN-17
CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC50 value of 9 nM, which can be used in cancer research[1].
Product Specifications
CAS Number
[451458-32-5]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1C2=C(N=C(N1C3=CC=C(CC)C=C3)SCC4=C(C)C=CC=C4)NN=C2
Molecular Formula
C21H20N4OS
Molecular Weight
376.47
References & Citations
[1]Wang T, et al. Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening[J]. European journal of medicinal chemistry, 2017, 129: 275-286.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK8
Available Sizes
Curated Selection
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