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GSK3β-IN-1

GSK3β-IN-1 (compound 1) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=65 nM), which can be used in the study of Alzheimer's disease[1].

Product Specifications

CAS Number

[757198-76-8]

UNSPSC

12352005

Target

GSK-3

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Neurological Disease

Smiles

FC1=CC(CSC2=NN=C(C3=CC4=C(OCO4)C=C3)O2)=CC=C1OC

Molecular Formula

C17H13FN2O4S

Molecular Weight

360.36

References & Citations

[1]Saitoh M, et al. Design, synthesis and structure-activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta. Bioorg Med Chem. 2009 Mar 1;17 (5) :2017-29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GSK-3β

Available Sizes

Curated Selection

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