Topoisomerase I/II inhibitor 7

Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor[1].

Product Specifications

CAS Number

[489413-54-9]

UNSPSC

12352005

Target

Topoisomerase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(N1N=C(CC1C2=CC=CO2)C3=CC=C(Cl)C=C3)C4=CC=CO4

Molecular Formula

C18H13ClN2O3

Molecular Weight

340.76

References & Citations

[1]Ahmad P, et al. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure–activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor[J]. Bioorganic & Medicinal Chemistry, 2016, 24 (8) : 1898-1908.