GPV574
GPV574 is a derivative of the antiarrhythmic compound propafenone, capable of inhibiting HERG channels (IC50 = 5.04 μM) .[1]
Product Specifications
CAS Number
635703-12-7
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
O=C(C)C1=CC=C(C=C1)OCC(CN2CCN(CC2)C3=CC=CC(C)=C3C)O
Molecular Formula
C23H30N2O3
Molecular Weight
382.50
References & Citations
[1]Windisch A, et al. Trapping and dissociation of propafenone derivatives in HERG channels[J]. British journal of pharmacology, 2011, 162 (7) : 1542-1552.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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