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RAD51-IN-9

RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C.

Product Specifications

CAS Number

103056-35-5

UNSPSC

12352005

Target

RAD51

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

O=C1C(Cl)=C(N2CCOCC2)C(N1C3=CC=CC=C3)=O

Molecular Formula

C14H13ClN2O3

Molecular Weight

292.72

References & Citations

[1]Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56 (1) :254-63.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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