RAD51-IN-9
RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C.
Product Specifications
CAS Number
103056-35-5
UNSPSC
12352005
Target
RAD51
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Smiles
O=C1C(Cl)=C(N2CCOCC2)C(N1C3=CC=CC=C3)=O
Molecular Formula
C14H13ClN2O3
Molecular Weight
292.72
References & Citations
[1]Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56 (1) :254-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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