Serotonin (maleate)
Serotonin hydrogen maleate is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrogen maleate is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM [1] [2].
Product Specifications
CAS Number
18525-25-2
Product Name Alternative
5-Hydroxytryptamine (maleate) ; 5-HT (maleate)
UNSPSC
12352005
Target
5-HT Receptor; COMT
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
NCCC(C1=C2)=CNC1=CC=C2O.OC(/C=C\C(O)=O)=O
Molecular Formula
C14H16N2O5
Molecular Weight
292.29
References & Citations
[1]Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25.|[2]Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8 (8) :e72774.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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