BCR-ABL-IN-11
BCR-ABL-IN-11 (Compound 2) is a BCR-ABL inhibitor. BCR-ABL-IN-11 shows anticancer activity against chronic myelogenous leukemia (CML) (IC50 of 129.61 μM for K562 cells) [1].
Product Specifications
CAS Number
[2362-25-6]
UNSPSC
12352211
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1)N)NC2=CC=CC(NC(C3=CC=C(C=C3)N)=O)=C2
Molecular Formula
C20H18N4O2
Molecular Weight
346.38
References & Citations
[1]Peng H, et al. Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening. Bioorg Med Chem Lett. 2003 Nov 3;13 (21) :3693-9.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169608/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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