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GSK-3β inhibitor 25

GSK-3β inhibitor 25 (Compound 6h) exhibits a weak inhibitory activity against GSK-3β wih an IC50>100 μM[1].

Product Specifications

CAS Number

[75620-25-6]

UNSPSC

12352005

Target

GSK-3

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Metabolic Disease; Neurological Disease

Smiles

O=C1N(CC2=CC=CC=C2)C3=C(SCC1)C=CC=C3

Molecular Formula

C16H15NOS

Molecular Weight

269.36

References & Citations

[1]Zhang P, et al., Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β) . Eur J Med Chem. 2013 Mar;61:95-103.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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