AZ513
AZ513 is a reversible FAAH inhibitor with an IC50s of 551 nM and 27 nM for human FAAH and rat FAAH, respectively. AZ513 inhibits Anandamide hydrolysis in human FAAH-transfected HEK293 cells (IC50 of 360 nM).
Product Specifications
CAS Number
1335231-15-6
UNSPSC
12352005
Target
FAAH
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
O=C(C1=C(Cl)C(Cl)=CC=C1)NC2=CC3=C(NC=C3)N=C2
Molecular Formula
C14H9Cl2N3O
Molecular Weight
306.15
References & Citations
[1]Scott CW, et al. Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase. Eur J Pharmacol. 2011 Sep 30;667 (1-3) :74-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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