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GSK-3β inhibitor 26

GSK-3β inhibitor 26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. GSK-3β inhibitor 26 can be used in the research of cancer, inflammation and neurodegenerative diseases[1].

Product Specifications

CAS Number

[70169-39-0]

UNSPSC

12352005

Target

GSK-3

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Smiles

O=C(C1=C(O)C=CC=C1)N/N=C2C(NC3=C\2C=CC=C3)=O

Molecular Formula

C15H11N3O3

Molecular Weight

281.27

References & Citations

[1]Dou X, et al. Discovery of new GSK-3β inhibitors through structure-based virtual screening. Bioorg Med Chem Lett. 2018 Jan 15;28 (2) :160-166.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GSK-3β

Available Sizes

Curated Selection

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