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PLK1-IN-11

PLK1-IN-11 (Cluster 4, 16953209) is a PLK1 inhibitor, with IC50 of 1 μM. PLK1-IN-11 can be used in research on a variety of cancers, including pancreatic, ovarian, breast, and non-small cell lung carcinoma[1].

Product Specifications

CAS Number

73663-97-5

UNSPSC

12352005

Target

Polo-like Kinase (PLK)

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

99.52

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=C(C=CC=C1)NC2=NC=NC3=C2NC=N3

Molecular Formula

C12H11N5O

Molecular Weight

241.25

References & Citations

[1]Sharlow ER, et al. Development and implementation of a miniaturized high-throughput time-resolved fluorescence energy transfer assay to identify small molecule inhibitors of polo-like kinase 1. Assay Drug Dev Technol. 2007 Dec;5 (6) :723-35.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PLK1

Available Sizes

Frequently Asked Questions

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