PLK1-IN-11
PLK1-IN-11 (Cluster 4, 16953209) is a PLK1 inhibitor, with IC50 of 1 μM. PLK1-IN-11 can be used in research on a variety of cancers, including pancreatic, ovarian, breast, and non-small cell lung carcinoma[1].
Product Specifications
CAS Number
[73663-97-5]
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
99.52
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C=CC=C1)NC2=NC=NC3=C2NC=N3
Molecular Formula
C12H11N5O
Molecular Weight
241.25
References & Citations
[1]Sharlow ER, et al. Development and implementation of a miniaturized high-throughput time-resolved fluorescence energy transfer assay to identify small molecule inhibitors of polo-like kinase 1. Assay Drug Dev Technol. 2007 Dec;5 (6) :723-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLK1
Available Sizes
Curated Selection
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