IGF-1R inhibitor-5

IGF-1R inhibitor-5 (compound 19) is a potent inhibitor of IGF-1R, with the IC50 of 6 μM. IGF-1R inhibitor-5 has the potential for the research of cancer[1].

Product Specifications

CAS Number

[331652-38-1]

UNSPSC

12352100

Target

IGF-1R

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C1S/C(C(N1)=O)=C/C2=CC=C(C3=C(Cl)C(Cl)=CC=C3)O2

Molecular Formula

C14H7Cl2NO3S

Molecular Weight

340.18

References & Citations

[1]East China University of Science and Technology, et al. Use of 5-substituted-2, 4-thiazolidinediones in preparation of medicaments for modulating insulin-like growth factor 1 receptor. World Intellectual Property Organization, WO2011063602 A1 2011-06-03