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EGFR-IN-149

EGFR-IN-149 (Compound 3-OH) is an EGFR inhibitor (IC50: 0.42 nM) [1].

Product Specifications

CAS Number

[401638-52-6]

UNSPSC

12352100

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

OC1=C(NC2=C3C(CCCC4)=C4SC3=NC=N2)C=CC=C1

Molecular Formula

C16H15N3OS

Molecular Weight

297.37

References & Citations

[1]Péter BÁNHEGYI, et al. Therapeutic application of triciclic aromatic and saturated benzo (4,5) thieno- (2,3-d) pyrimidine derivates, as well as their therapeutically acceptable salts. Patent. WO2009104027 A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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