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PKM2-IN-9

PKM2-IN-9 (compound C1) is a potent inhibitor of PKM2, with the inhibition rate of 75% at 50 μM. PKM2-IN-9 plays an important role in cancer research[1].

Product Specifications

CAS Number

498568-75-5

UNSPSC

12352005

Target

Pyruvate Kinase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C(C1=CC=CC=C1)NCC2=NC3=C(N2CC(NC4=CC=CC(C)=C4)=O)C=CC=C3

Molecular Formula

C24H22N4O2

Molecular Weight

398.46

References & Citations

[1]Beth Israel Deaconess Medical Center. Pyruvate kinase M2 inhibitors and methods using them for the treatment of disease. World Intellectual Property Organization, WO2008019139 A2 2008-02-14

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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