EGFR-IN-146
EGFR-IN-146 is an EGFR inhibitor that can inhibit the EGFR signaling pathway and improve insulin sensitivity by activating the AMPK pathway, which can effectively reduce blood sugar levels and body weight. EGFR-IN-146 has great potential in the study of diabetes and obesity[1].
Product Specifications
CAS Number
[166039-38-9]
UNSPSC
12352005
Target
AMPK; EGFR
Related Pathways
Epigenetics; JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Field of Research
Metabolic Disease
Smiles
C1(CNC2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)=CC=CN=C1
Molecular Formula
C20H16N4
Molecular Weight
312.37
References & Citations
[1]Nam Kyu Lee, et al. Quinazoline derivatives for the treatment and prevention of diabetes and obesity . WO2006071095A1.JP.2005-12-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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