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EGFR-IN-146

EGFR-IN-146 is an EGFR inhibitor that can inhibit the EGFR signaling pathway and improve insulin sensitivity by activating the AMPK pathway, which can effectively reduce blood sugar levels and body weight. EGFR-IN-146 has great potential in the study of diabetes and obesity[1].

Product Specifications

CAS Number

166039-38-9

UNSPSC

12352005

Target

AMPK; EGFR

Related Pathways

Epigenetics; JAK/STAT Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK

Field of Research

Metabolic Disease

Smiles

C1(CNC2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)=CC=CN=C1

Molecular Formula

C20H16N4

Molecular Weight

312.37

References & Citations

[1]Nam Kyu Lee, et al. Quinazoline derivatives for the treatment and prevention of diabetes and obesity . WO2006071095A1.JP.2005-12-30.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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