CDK8-IN-18
CDK8-IN-18 (compound BRD-2299) is a potent inhibitor of CDK8, with the IC50 of 43 μM. CDK8-IN-18 plays an important role in cancer research[1].
Product Specifications
CAS Number
[642002-74-2]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
N#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N
Molecular Formula
C16H18N4
Molecular Weight
266.34
References & Citations
[1]The Broad Institute, Inc., et al. Use of CDK8 inhibitors to treat diseases of inflammation and autoimmunity. World Intellectual Property Organization, WO2018027082 A1 2018-02-08
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
148212 100 µg
NANOG, Control Peptide (Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, hNanog, FLJ12581, FLJ40451)
Ask
View Details 