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CDK8-IN-18

CDK8-IN-18 (compound BRD-2299) is a potent inhibitor of CDK8, with the IC50 of 43 μM. CDK8-IN-18 plays an important role in cancer research[1].

Product Specifications

CAS Number

642002-74-2

UNSPSC

12352005

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

N#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N

Molecular Formula

C16H18N4

Molecular Weight

266.34

References & Citations

[1]The Broad Institute, Inc., et al. Use of CDK8 inhibitors to treat diseases of inflammation and autoimmunity. World Intellectual Property Organization, WO2018027082 A1 2018-02-08

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK8

Frequently Asked Questions

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