VEGFR/PDGFR-IN-1
VEGFR/PDGFR-IN-1 (Compound 1) is the inhibitor for VEGFR with an IC50 of 0.4 μM. VEGFR/PDGFR-IN-1 inhibits angiogenesis in HUVEC cell, exhibiting potential in tumor growth and metastasis inhibition[1].
Product Specifications
CAS Number
[342785-98-2]
UNSPSC
12352005
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C1C2=C(N(C)C(N1C)=O)N=CN2CC(CNC3=CC=CC(C)=C3)O
Molecular Formula
C17H21N5O3
Molecular Weight
343.38
References & Citations
[1]Rathinavelu A, et al., Specific inhibitors for vascular endothelial growth factor receptors. US20080139585
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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