VEGFR-2-IN-65
VEGFR-2-IN-65 (Compound 07) is a VEGFR-2 inhibitor. VEGFR-2-IN-65 has H-bond interactions with Cys180. VEGFR-2-IN-65 inhibits tube formation in HUVECs[1].
Product Specifications
CAS Number
371213-22-8
UNSPSC
12352005
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
OC1=C(C2=NNC(C3=CC(OC)=C(OC)C=C3)=C2)C=CC4=C1C=CC=C4
Molecular Formula
C21H18N2O3
Molecular Weight
346.38
References & Citations
[1]Zhang L, et al. Discovery of novel vascular endothelial growth factor receptor 2 inhibitors: a virtual screening approach. Chem Biol Drug Des. 2012 Dec;80 (6) :893-901.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Frequently Asked Questions
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