VEGFR-2-IN-65

VEGFR-2-IN-65 (Compound 07) is a VEGFR-2 inhibitor. VEGFR-2-IN-65 has H-bond interactions with Cys180. VEGFR-2-IN-65 inhibits tube formation in HUVECs[1].

Product Specifications

CAS Number

[371213-22-8]

UNSPSC

12352005

Target

VEGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

OC1=C(C2=NNC(C3=CC(OC)=C(OC)C=C3)=C2)C=CC4=C1C=CC=C4

Molecular Formula

C21H18N2O3

Molecular Weight

346.38

References & Citations

[1]Zhang L, et al. Discovery of novel vascular endothelial growth factor receptor 2 inhibitors: a virtual screening approach. Chem Biol Drug Des. 2012 Dec;80 (6) :893-901.