TrkA-IN-8
TrkA-IN-8 (Compound 2) is a TrkA inhibitor with a Kd value of 3.3 µM. RTKs-IN-1 exhibits concentration-dependent inhibition of cell proliferation in lung cancer cell lines. RTKs-IN-1 holds potential for research in non-small cell lung cancer [1].
Product Specifications
CAS Number
[128889-33-8]
UNSPSC
12352005
Target
Trk Receptor
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
NC1=CC2=C(C3=CC=CC=C3)N=C(C4=CC=C(N)C=C4)N=C2C=C1
Molecular Formula
C20H16N4
Molecular Weight
312.37
References & Citations
[1]Kim J Y, et al. Effects of Tropomyosin-related kinase a inhibitors on the proliferation of human lung cancer cells[J]. Bulletin of the Korean Chemical Society, 2013, 34 (4) : 1293-1295.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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