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Aurora kinase inhibitor-13

Aurora kinase inhibitor-13 (Compound 2) is an inhibitor of Aurora kinase, with an IC50 value of 2.3 μM against Aurora kinase A[1].

Product Specifications

CAS Number

[792965-51-6]

UNSPSC

12352005

Target

Aurora Kinase

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(CN1C(NC(CC)(CC)C1=O)=O)OCC(N=C2SC3=C(N24)C=CC=C3)=CC4=O

Molecular Formula

C20H20N4O5S

Molecular Weight

428.46

References & Citations

[1]Bogolubsky A V, et al. An old story in the parallel synthesis world: an approach to hydantoin libraries[J]. ACS Combinatorial Science, 2018, 20 (1) : 35-43.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Aurora A

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