Pantothenate-AMC
Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively[1].
Product Specifications
CAS Number
[1224691-12-6]
UNSPSC
12352211
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Metabolic Disease
Purity
99.2
Smiles
CC(C1=CC=C(NC(CCNC([C@H](O)C(C)(C)CO)=O)=O)C=C1O2)=CC2=O
Molecular Formula
C19H24N2O6
Molecular Weight
376.40
References & Citations
[1]Ruan BH, et al. A fluorescent assay suitable for inhibitor screening and vanin tissue quantification. Anal Biochem. 2010 Apr 15;399 (2) :284-92.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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