PDIC-NC

PDIC-NC is a STING agonist. PDIC-NC is cytotoxic to tumor cells and induces ROS explosion, apoptosis and autophagy. PDIC-NC has lung specific distribution and can be used in the study of lung cancer[1][2].

Product Specifications

CAS Number

[2633013-75-7]

UNSPSC

12352005

Target

Apoptosis; Autophagy; Reactive Oxygen Species (ROS) ; STING

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Cancer

Smiles

O=C1C2=CC(Cl)=C3C4=C(C=C5C(N(CCN(C)C)C(C6=CC(Cl)=C(C4=C56)C7=C3C2=C(C(N1CCN(C)C)=O)C=C7Cl)=O)=O)Cl.Cl.Cl

Molecular Formula

C32H26Cl6N4O4

Molecular Weight

743.29

References & Citations

[1]Liu Z, et al. Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angew Chem Int Ed Engl. 2021 Jul 12;60 (29) :16215-16223.|[2]Zhao X, et al. Sulfonated Perylene as Three-in-One STING Agonist for Cancer Chemo-Immunotherapy. Angew Chem Int Ed Engl. 2024 Mar 11;63 (11) :e202318799.