PDIC-NC
PDIC-NC is a STING agonist. PDIC-NC is cytotoxic to tumor cells and induces ROS explosion, apoptosis and autophagy. PDIC-NC has lung specific distribution and can be used in the study of lung cancer[1][2].
Product Specifications
CAS Number
2633013-75-7
UNSPSC
12352005
Target
Apoptosis; Autophagy; Reactive Oxygen Species (ROS) ; STING
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
O=C1C2=CC(Cl)=C3C4=C(C=C5C(N(CCN(C)C)C(C6=CC(Cl)=C(C4=C56)C7=C3C2=C(C(N1CCN(C)C)=O)C=C7Cl)=O)=O)Cl.Cl.Cl
Molecular Formula
C32H26Cl6N4O4
Molecular Weight
743.29
References & Citations
[1]Liu Z, et al. Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angew Chem Int Ed Engl. 2021 Jul 12;60 (29) :16215-16223.|[2]Zhao X, et al. Sulfonated Perylene as Three-in-One STING Agonist for Cancer Chemo-Immunotherapy. Angew Chem Int Ed Engl. 2024 Mar 11;63 (11) :e202318799.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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