ALK protein ligand-1
ALK protein ligand-1 (Compound A1), a ligand for the anaplastic lymphoma kinase (ALK) protein, is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that exhibits inhibitory effects on ALK. ALK protein ligand-1 can be used in the synthesis of AP-1.
Product Specifications
CAS Number
2764870-80-4
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK) ; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=S(C1=C(NC2=NC(NC3=CC=C(N4CCNCC4)C=C3OC)=NC=C2Cl)C=CC=C1)(C(C)C)=O
Molecular Formula
C24H29ClN6O3S
Molecular Weight
517.04
References & Citations
[1]Lidong Gong, et al. Discovery of a miniaturized PROTAC with potent activity and high selectivity. Bioorg Chem. 2023 Jul:136:106556.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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