ALK protein ligand-1

ALK protein ligand-1 (Compound A1), a ligand for the anaplastic lymphoma kinase (ALK) protein, is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that exhibits inhibitory effects on ALK. ALK protein ligand-1 can be used in the synthesis of AP-1 (HY-169481) [1].

Product Specifications

CAS Number

[2764870-80-4]

UNSPSC

12352005

Target

Anaplastic lymphoma kinase (ALK) ; Ligands for Target Protein for PROTAC

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=S(C1=C(NC2=NC(NC3=CC=C(N4CCNCC4)C=C3OC)=NC=C2Cl)C=CC=C1)(C(C)C)=O

Molecular Formula

C24H29ClN6O3S

Molecular Weight

517.04

References & Citations

[1]Lidong Gong, et al. Discovery of a miniaturized PROTAC with potent activity and high selectivity. Bioorg Chem. 2023 Jul:136:106556.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 4

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