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Starburst 1st generation (13.93% w/w in water)

Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells[1].

Product Specifications

CAS Number

142986-44-5

Product Name Alternative

PAMAM G1.0

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(CCN(CCC(NCCN)=O)CCNC(CCN(CCN(CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)CCC(NCCN(CCC(NCCN)=O)CCC(NCCN)=O)=O)=O)NCCN

Molecular Formula

C62H128N26O12

Molecular Weight

1429.85

References & Citations

[1]Ender Sarigul, et al. Polyamidoamine Dendron-Bearing Lipids as Drug-Delivery Excipients. Molecules. 2022 Nov 13;27 (22) :7817.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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