(-) -9-Hydroxycorynantheidine
(-) -9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine), the 9-demethyl analogue of Mitragynine, is a selective and partial agonist of μ-opioid receptor. (-) -9-Hydroxycorynantheidine inhibits electrically stimulated twitch contraction in guinea-pig ileum[1].
Product Specifications
CAS Number
[425623-55-8]
Product Name Alternative
9-O-Desmethyl mitragynine
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
COC(/C([C@H]1C[C@@]2([H])C3=C(CCN2C[C@H]1CC)C4=C(O)C=CC=C4N3)=C/OC)=O
Molecular Formula
C22H28N2O4
Molecular Weight
384.47
References & Citations
[1]Matsumoto K, et al. Partial agonistic effect of 9-hydroxycorynantheidine on mu-opioid receptor in the guinea-pig ileum. Life Sci. 2006 Apr 4;78 (19) :2265-71.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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