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GSK-364735 (sodium)

GSK-364735 sodium (S/GSK-364735 sodium) is the sodium salt form of GSK-364735. GSK-364735 sodium is an antiretroviral, that inhibits the integrase of human immunodeficiency virus type 1 (HIV-1) with an IC50 of 7.8 nM[1].

Product Specifications

CAS Number

863437-78-9

Product Name Alternative

S/GSK-364735 (sodium)

UNSPSC

12352005

Target

HIV; HIV Integrase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C1=C(O)C2=C(C=C(CC3=CC=C(C=C3)F)C=N2)N(C)C1=O)NCCO.[Na]

Molecular Formula

C19H18FN3NaO4

Molecular Weight

394.35

References & Citations

[1]Garvey EP, et al., The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother. 2008 Mar;52 (3) :901-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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